Dawson's Creek cast reunite for one night only to support James Van Der Beek's cancer battle

It's a moment Dawson's Creek fans have waited 22 years for.

The cast are finally reuniting but it's not on the telly - they're coming together for one night only for a special event to honour Dawson Leery himself, James Van Der Beek.

Van Der Beek will be joined by former co-stars Katie Holmes, Michelle Williams and Joshua Jackson for a live script reading of the show's pilot next month on Broadway in New York City in support of charity F Cancer.

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Van Der Beek, who opened up about being diagnosed with colorectal cancer last November, shared a snapshot of the core four cast members to his Instagram on Wednesday (Thursday AEST).

The image was set to the opening lyrics of Paula Cole's I Don't Want to Wait, which famously served as the teen soap's theme song.

Alongside the polaroid image there was a quote from the final episode of the show, which aired in 2003, after running for six seasons.

"If we were truly meant to be, then we will find a way back to each other," it read.

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The event, titled Dawson's Creek Class Reunion, will take place on September 22 at the Richard Rodgers Theatre.

In addition to the core cast, Mary Beth Peil, Kerr Smith, Meredith Monroe and Busy Phillips will also perform in the reading.

Van Der Beek said in November that he was battling stage 3 cancer, which he said he had been dealing with privately until a tabloid shared plans to run a story about it.

He later opened up at length to People magazine about his ordeal.

Dawson's Creek debuted on (US network) the WB in 1998 and followed a group of teens in fictional Capeside, Massachusetts as they navigated friendship, love and ambitions in school and beyond, led by Van Der Beek's titular film nerd character. The show veritably launched the careers of the main foursome.

Tony-nominee Williams and Dawson's Creek show creator Kevin Williamson are among the producers of the live reading.

F Cancer is a nonprofit organisation that advances health equity through early cancer detection and prevention, and provides resources to navigate, manage and cope with cancer, according to its website.

- Reported with CNN.

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