John Stamos' three-word response when asked if he'd leave his wife for Full House co-star Lori Loughlin
John Stamos didn't hold back when he was asked a rather awkward question during a podcast interview.
The American actor, 62, was on the Good Guys Podcast when the hosts asked a listener question about his relationship with Full House co-star Lori Loughlin.
Stamos is married to Caitlin McHugh, but touched on his relationship with Loughlin during the interview in the wake of her split from Mossimo Giannulli.
Watch the video above.
John Stamos had a fiery response when asked if he'd leave his wife for Full House co-star Lori Loughlin. Getty
"The biggest question was, 'Come on, Aunt Becky [Loughlin's Full House character], bring her in. Bring her into the fold'," one of the hosts said.
"A threesome?" Stamos responded.
The host replied, "That wasn't what they asked. They asked if you'd leave your wife for her. We're not doing that."
"No f--king way!" Stamos shot back.
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"They asked if you'd leave your wife for her. We're not doing that." YouTube
"I'm not Mormon. Do you do that with your wife? Are you a swinger?"
Stamos and the hosts then laughed off the remarks.
He also touched on their relationship earlier and said that Loughlin was ''too nice'' for him.
"A lot of people [would say], 'oh, you guys were romantic or what,'" he said.
"I happened to say she was the one that got away in something and, you know, I think it was before I met Caitlyn.
"I was more into the rebellious. Lori was so sweet and I loved working with her, but it was just too, she was too nice for me."
On the podcast, he also described Loughlin's divorce as "heartbreaking" for her before explaining he was not very fond of Giannulli.
"He's a very successful dude... [but] I will never talk to him again, he's a terrible narcissist," Stamos claimed.
"She put up with a lot over the years of this guy ... I was by her side through a lot of it."
Giannulli and Loughlin were married for 28 years before announcing their split earlier this month.
The pair first met in a Los Angeles restaurant in 1995. After dating for two years, they eloped in 1997.
They welcomed their first daughter, Isabella, in September 1998, followed by Olivia Jade nearly exactly a year later.
The celebrity couple's marriage famously weathered a run-in with the law.
Mossimo Giannulli and Loughlin were married for 28 years before announcing their split. WireImage
They both pleaded guilty to conspiracy to commit wire and mail fraud after being accused of giving $500,000 to the University of Southern California to get their daughters into college.
The couple had initially pleaded not guilty to the fraud charges.
Both girls were falsely classified as athletic recruits for the college's team, despite never participating in the sport.
Loughlin was sentenced to two months in federal prison, while her husband was sentenced to five months.
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