Vic man killed in targeted attack: police

A man has died after an execution-style shooting in Melbourne's southwest.

Police say a 39-year-old man, reported to be a father of six, was shot numerous times while sitting in a car in his mother's Altona Meadows driveway about 2am on Sunday.

Homicide Detective Sergeant Sol Solomon said while no eyewitnesses to the shooting had come forward, neighbours reported hearing screeching tyres soon after shots were fired.

Police believe the attack was targeted and confirmed the victim was known to police.

The man's mother and several other family members who were in the house at the time are assisting police with their investigation, Detective Solomon says.

No one has been arrested over the shooting.