Mother-of-seven dies following suspicious Melbourne house fire

A mother-of-seven has died four days after her home in Melbourne's west went up in flames while she and a number of her children were inside.

Kylie Griffiths, 36, was rushed to The Alfred Hospital with critical burns after the fire occurred at her home on Sutherland Street, Albanvale just before 5.30pm on Monday.

She died from her injuries early this morning, according to Victoria Police.

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A 17-year-old girl also suffered burns from the fire and taken to The Royal Hospital.

Ms Griffith's husband, 38-year-old Roland Griffiths, was also taken to The Alfred Hospital with serious injuries.

He remains under police guard in hospital as police investigate the fire, which has been deemed suspicious.