Pdrn what is it best serums products to shop trend explainer 20260602 p6039o.html – Breaking News & Latest Updates 2026
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PDRN is everywhere right now, but do you need to buy it?

Lisa Panetta
Lisa Panetta

Updated

Medik8 Exo-PDRN Prismatic+

If you've been seeing the term PDRN everywhere, you're not alone. Medik8

As a beauty writer, I’ve seen my fair share of skincare trends do the rounds. From the rise of at-home LED devices to skin slugging, the latest trend to hit the market is PDRN, also referred to as ‘salmon sperm’. 

While a quick social media search confirms that this ingredient is absolutely trending right now – thanks to Anua PDRN Hyaluronic Acid Capsule 100 Serum landing on Aussie shores earlier this year – it has actually been around for almost 50 years. 

Anua PDRN Hyaluronic Acid Capsule 100 Serum

The Anua PDRN Hyaluronic Acid Capsule 100 Serum.

The Anua PDRN Hyaluronic Acid Capsule 100 Serum has gone viral across social media since its Australian launch in February.  Anua

Originating in Italy in the 1990s, PDRN (polydeoxyribonucleotide) was used for wound healing and skin regeneration. By 2010, this ingredient was adopted by Korean dermatologists in the injectable space before it was formulated for topical products like serums and lotions. 

The Korean beauty market has been the primary driver of PDRN’s popularisation, and with K-beauty notoriously well-priced, getting your hands on it is far more affordable than you think.

So, if you’re ready to shop the trend, here’s what you need to know about PDRN.  

What is PDRN?

According to a 2022 study led by researcher Aawrish Khan, PDRN is made up of microscopic DNA fragments that are typically derived from salmon or trout. 

The study also noted that because this purified DNA is most compatible with humans, our body can easily recognise and react to the DNA fragments, triggering the body to kickstart its collagen production without causing any reaction or irritation. 

Medicube PDRN Pink Peptide Serum

The Medicube PDRN Pink Peptide Serum is another fan favourite.

The Medicube PDRN Pink Peptide Serum is another fan favourite.  Medicube

While this type of PDRN is the most common in the skincare world, there has been a huge increase in vegan alternatives that are derived from plant compounds that mimic the fragments found in the salmon DNA. 

Vt Cosmetics PDRN 100 Essence

The Vt Cosmetics PDRN 100 Essence is a great vegan option.

The Vt Cosmetics PDRN 100 Essence is a great vegan option.  VT Cosmetics

What is PDRN best used for? 

Khan’s study further revealed that this ingredient is said to help speed up the skin’s healing process, while also helping to support the reduction of inflammation. 

Because of the DNA-based nature of this ingredient, it is safe for all skin types; however, it’s recommended to watch out for other ingredients it might be formulated with. 

If your skin is oily and acne-prone, opt for something like the Innisfree Retinol Green Tea PDRN Skin Booster Ampoule or the Medik8 Exo-PDRN Prismatic+, as they are each formulated with a more lightweight, water-like texture.

Innisfree Retinol Green Tea PDRN Skin Booster Ampoule

Innisfree Retinol Green Tea PDRN Skin Booster Ampoule.

Innisfree Retinol Green Tea PDRN Skin Booster Ampoule. Innisfree

Medik8 Exo-PDRN Prismatic+

Medik8 Exo-PDRN Prismatic+.

Medik8 Exo-PDRN Prismatic+. Medik8

If you’re someone who loves to lather on an ultra-rich cream, then something like the Anua Hyaluronic Acid 100 Moisture Cream or the Numbuzin No.2 Rose PDRN Collagen 2X Plumping Serum might be more to your liking.

Auna PDRN Hyaluronic Acid 100 Moisture Cream 

Auna PDRN Hyaluronic Acid 100 Moisture Cream.

Auna PDRN Hyaluronic Acid 100 Moisture Cream. Anua

Numbuzin, No.2 Rose PDRN Collagen 2X Plumping Serum

Numbuzin, No.2 Rose PDRN Collagen 2X Plumping Serum.

Numbuzin, No.2 Rose PDRN Collagen 2X Plumping Serum. Numbuzin

READ MORE: Six affordable Korean and Japanese beauty products you must try

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