Melissa McCarthy responds to Barbra Streisand's Ozempic comment: 'I win the day'

Melissa McCarthy remains a proud fan of Barbra Streisand.

The Oscar-nominated actress seems completely unbothered by a comment Streisand left on her Instagram, in which the legendary singer asked McCarthy if she was on Ozempic.

In fact, she took it as a complement.

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McCarthy shared her response in a clip posted to Instagram late on Tuesday (Wednesday AEST), holding a magazine with a vintage picture of Streisand on the cover.

"@barbrastreisand fan club members only!!!," she captioned the post.

In the short video, the Bridesmaid star said she was just thrilled the singer, affectionately known as Babs, knew she existed - despite the pair having performed together before.

"The takeaway is Barbra Streisand knows I exist. She reached out to me and she thought I look good!" McCarthy said in a short video.

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"I win the day," she added.

McCarthy's post came after Streisand wrote and then deleted her question to McCarthy about the weight-loss medication.

Streisand addressed her comment, saying she initially opened her Instagram to look at photos of the "beautiful flowers" she'd received for her birthday last week.

"Below them was a photo of my friend Melissa McCarthy who I sang with on my Encore album," she wrote.

"She looked fantastic! I just wanted to pay her a compliment. I forgot the world is reading!"

Their mutual admiration remains.

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