Kathy Griffin's sister Joyce loses her battle with cancer at age 65

Kathy Griffin has said goodbye to her sister, Joyce, after she passed away from cancer.

The 56-year-old shared a heartfelt video tribute on Instagram Friday, revealing that her sister had died Thursday night at the age of 65. 

In the video, Joyce appears in a hospital bed and wears a pink beanie as she listens to a singer who stands in the doorway of her hospital room.

Alongside the video, the comedian captured the post, "My sister Joyce passed away peacefully last night. Check out this beautiful moment. Please support American Cancer Society Society here: goo.gl/eMJVhq (Link In Bio)." 

The video concludes with a touching slideshow, and the words: "This is where she always wanted to be … & now she’s having a mai tai on the beach in heaven," alongside an illustration of her sister relaxing at the beach.

In July, Kathy shaved her head to stand in solidarity with her sister who was undergoing chemotherapy at the time.

The second photo shows the comedian sitting beside her mum, Maggie Griffin, who covers her mouth in surprise. Maggie later tweeted that her daughter "Kathleen Mary is a wonderful human being."

It is not clear what type of cancer Joyce was suffering from.

In 2014, the star’s older brother, Gary, passed away from stage-four esophageal cancer at the age of 63. "This AM my brave brother Gary Griffin passed away in palliative care after a brutal struggle w cancer," she wrote in an Instagram post which has since been deleted. "Oh & he was funny as s---."