Woman dies, two others injured after five-vehicle crash in Melbourne

A woman has died and two other people have been hospitalised after a five-vehicle crash in Melbourne's north.

Police said today investigators are still trying to determine the cause of the crash on High Street in Reservoir about 7.15pm on Monday as they urged drivers to take care amid a rising Victorian road toll.

The woman died at the scene after losing control of her car and crashing into other vehicles, damaging up to seven.

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Two other people were taken to hospital with serious injuries while others were treated at the scene by emergency services.

About 143 people have died on the road this year, an increase of 34.9 per cent from this time last year.

"Everyone needs to slow down and concentrate on their driving and be respectful to other drivers," Victoria Police Sergeant Ashley Hodge said .

"We don't want to come to these things, it affects everyone (including) the first responders."

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