Vic woman survives second quake

A Victorian woman who narrowly avoided April's Kathmandu earthquake by hours felt "extremely vulnerable" during the latest Nepalese quake.

The 7.30-magnitude quake hit in the early afternoon in an isolated, conservation area between Kathmandu and Mount Everest, killing at least 42 people.

It was followed by a series of lesser aftershocks measuring from 5.6 to 6.3 in magnitude.

Amanda Delecca, a Kathmandu-based tourism operator originally from Bendigo, told AAP she was planning a late lunch at a local deli which lost over 400 bottles of wine in the April quake, when the "violent" tremors began.

She dived under the kitchen table of her third floor apartment.

"Although my house has endured the tremors until now, I felt extremely vulnerable being on the third floor," she said.

"My friends who live out of town... could see the plumes of dust come up from the earth where houses have gone down.

"My friends estimate there were at least 40 houses that are no longer. A sight to behold."

Ms Delecca managed to avoid the 25 April quake when she left the nation's capital for a work trip, just hours before it struck.

Nepal's national emergency operation centre said on Twitter that 335 people have been injured in the quake.