Van with special-needs teens in Vic crash

Two special-needs teenagers and a carer have been injured on an excursion to Melbourne after their mini-bus collided with a tram and crashed into a CBD building.

The carer driving the mini-bus - a women in her 20s - had to be freed by firefighters after suffering head, neck and chest injuries in the crash, emergency services said on Thursday.

She had been making a hook turn from Collins Street about 10.45pm on Wednesday when a tram crashed into the side of the mini-bus and pushed it 100 metres down the road.

The bus then collided with a parked car, mounted the gutter and crashed into a pillar of a building, police said.

Two of the four special-needs teenagers on the bus suffered arm and facial injuries and were taken to hospital in a stable condition.

The tram driver was also assessed at the scene, Ambulance Victoria said.

The teenagers, aged 15 to 17, are students at a Bass Coast school and had been in Melbourne on a school camp.