Homicide looks for missing Vic woman

A mother of four is missing from her home in regional Victoria, prompting the homicide squad to investigate the out-of-character disappearance.

Samantha Kelly, 39, was last seen around the High Street shopping strip in the Bendigo suburb of Kangaroo Flat about 3.20pm on Wednesday January 20, police say.

There are unconfirmed reports Ms Kelly was seen a number of times between that date and January 23.

"The disappearance of the mother of four is out of character and investigators would like to hear from anyone who may be able to provide details of her whereabouts," a Victoria Police spokeswoman said.

Detectives have released images of Ms Kelly, and are asking anyone with information to phone Crime Stoppers.