North Qld the winner from MP's resignation

Influential crossbencher Rob Katter has warned Premier Annastacia Palaszczuk she will be forced out if she stands in the way of his growing north Queensland parliamentary alliance.

A north Queensland voting bloc has grown to four with Cairns MP Rob Pyne's resignation from Labor's minority government to sit on the crossbenches.

He joins the two Katter's Australian Party MPs - Mr Katter and Shane Knuth - and another former Labor MP turned Independent, Cooktown-based Billy Gordon.

Mt Isa-based Mr Katter admitted the quartet would be silly not to join forces to get the best result for the "sadly neglected" regional and rural areas of their electorates.

"It's not a surprise to me that someone from the north (Mr Pyne) feels disenfranchised by the major parties because it's a common affliction there in parliament in Brisbane," he told AAP.

"The upshot of this is it's good news for Queensland because we have a strengthened and invigorated crossbench.

"For a rare point in our lifetimes we'll have an opportunity for rural and regional areas of Queensland to have some influence and repair some neglect that's been very detrimental to the wider economy for the last 25 years."

Mr Katter cited the KAP's sugar marketing bill, which passed parliament in December, as an example of how a crossbench could trigger action despite both major parties aiming to implement change for a decade.

Political analyst Paul Williams was quick to hail north Queensland as the big winner from Mr Pyne's decision which leaves Labor and the Liberal National Party deadlocked with 42 seats in the 89-seat parliament.

Dr Williams said the region had rightly felt ignored by the government in recent times.

Ms Palaszczuk on Tuesday threatened she wouldn't hesitate to call an early election if any MPs stand in her way of delivering jobs to Queensland.

Mr Katter returned serve by saying the northern MPs were more determined to see the development - particularly infrastructure to open up the northwest mineral province - that's warranted to deliver both employment opportunities and tax revenue.

"If she's consistent with what she said she won't have a problem at all," he said

"We don't want walkways, footbridges or monorails. We want industry-enabling infrastructure that residents in Brisbane will be a lot bigger beneficiaries than us.

"This is good news for Queensland and the premier should embrace the opportunity with both arms. If not she should get out of the way and let someone else have a go.

"If not the government has got a problem."