Nurse tried to help shot Melbourne man

Neighbours of a man who has been shot dead in Melbourne say they tried to save him.

Police discovered the man's body when they went to an address in Epping in the city's north to investigate reports of gunshots being heard just after 11pm on Saturday.

They also found a second man with leg injuries that are not life threatening.

The man's neighbour, nurse Debbie Tuckerman called police when she heard about six shots being fired.

She then put her medical training into action.

"I just immediately went over there, tried to find a pulse. Couldn't find it ... we all did our best," she told ABC Radio. Mrs Tuckerman's husband Gary said the man had been shot in the chest.

"I do know him, he's a good bloke," he said.

It's believed a number of offenders may have fled on foot after the shooting.

Police are urging anyone with information to contact Crime Stoppers on 1800 333 000 or www.crimestoppers.com.au