Two brothers from one family fatally stabbed in Melbourne six months apart

One family has lost two sons in just six months after a man was fatally stabbed in Melbourne's west last night.

Kon Kot - whose brother Machar Kot was killed in June - has followed the tragic fate of his brother, dying after being stabbed at a Hungry Jack's in Caroline Springs last night.

Mr Kot's family claim he went to the fast food restaurant about 9pm after he received a panicked call from his 15-year brother, who was allegedly being threatened with a knife when the 24-year-old arrived.

A fight broke out which grew out of control and Mr Kot was stabbed.

Paramedics were called but the Kurunjang man died at the scene.

James Makir, 24, was arrested at a nearby house has been charged with one count of murder. He faced the Melbourne Magistrates' Court today.

Another man was also arrested and later released from custody.

Investigators have conducted a line search for the weapon along with a police helicopter.

Police believe Mr Makir and Mr Kot knew each other.

Mr Kot's family gathered in grief at the Kuranjang home today, remembering a young man who lived for his family and never truly coped with the loss of his younger brother, Machar.

Anybody with any further information is urged to contact Crime Stoppers on 1800 333 000.