'MH370 is lost, none survived'

Malaysia Airlines has announced the missing Boeing 777 is assumed to have crashed with no survivors.

"We deeply regret that we have to assume beyond any reasonable doubt that MH370 has been lost and that none of those on board have survived," the airline said in a statement.

"We must now accept all evidence suggests the plane went down in the Southern Indian Ocean."

The airline made the statement after calling an urgent meeting in Beijing at 12.30am AEDT for families of those on the Boeing 777, which went missing on March 8.