Four injured in stabbing attack at Frankfurt train station

At least one person is on the run after allegedly stabbing four people at a train station in Frankfurt, Germany.

Police have confirmed four people are in hospital after they were stabbed with pieces of broken glass during an attack at Hauptwache train station in Frankfurt, local news outlet Hessenschau reports.

The scene has been cordoned off while police try to determine whether one or more people are responsible for the attack.

The exact condition of those in hospital remains unknown, as does the motive for the attack.

Frankfurt Police have asked the public to refrain from speculation and fear-mongering.

"We are asking to refrain from speculation... You are scaring your fellow citizens. There is no danger," a tweet to their official account said.

It is believed the incident took place on at least two different platforms after police found blood in two different areas.

Download the 9NEWS Alerts app for iPhone or Android to get push notifications when a major story breaks near your location.