Smoothie blamed for mass allergic reaction at Melbourne creche

A smoothie is being blamed as a potential cause of a mass allergic reaction at a Melbourne child-minding service.

Parents were told their children couldn't leave Chabad House in Caulfield as paramedics assessed more than a dozen affected.

"We're only making assumptions ... possibly something in the smoothie they were drinking," Jo Wilton from Ambulance Victoria said.

None of the children required hospital treatment.

Approximately 18 firefighters responded to the outbreak.

Fire Rescue Victoria crews were called to the Glen Eira Road incident just after 4.05pm.

"A caller to Triple Zero reported multiple occupants suffering a suspected reaction to an unknown substance," FRV said in a statement.

"Firefighters arrived on scene in six minutes and worked quickly to establish the source of the reactions.

"Crews identified there was no Hazmat risk, and the likely cause of the reaction was through a food source."

Victoria police and local council also attended the creche.