NSW man dies as packed car hits tree

A young man has died after a small car packed with five men veered off the road and hit a tree in Canley Vale.

The two-door car left the road near Cathcart Street, in Sydney's southwest, and crashed after midnight.

Police say the man, believed to be in his 20s, died at the scene.

The four other men have been taken to Liverpool Hospital, with two in a serious condition.

It's not yet known who was driving the car.

Railway Parade was closed in both directions near Cathcart Street for several hours on Sunday morning.

Police are appealing for anyone who witnessed the crash to come forward.

A brief will be prepared for the coroner.