Two dead after multi-vehicle crash

Two people have died and three others were injured in Brisbane after a multi-vehicle crash.

Police and paramedics were called to the crash involving four cars and a motorbike overnight at Lutwyche Rd in the northern suburb of Windsor.

Two people were declared dead at the scene. Three other victims were taken to hospital with non-life-threatening injuries.

Lutwyche Rd is now clear for vehicles travelling in both directions after it was closed for several hours.

The police forensic crash unit is investigating the crash.